Monkeypox Virus Antibody Rapid Test – Product code: SC-2368-25.
A rapid test for the qualitative detection of antibodies to Monkeypox Virus in human whole blood, serum or plasma. For professional in vitro diagnostic use only. The Monkeypox Virus Antibody Rapid Test is a lateral flow chromatographic immunoassay for the qualitative detection of antibodies to Monkeypox Virus in whole blood, serum or plasma to aid in the diagnosis of Monkeypox Virus infection. Monkeypox is a zoonotic orthopoxvirus that incidentally causes disease in humans similar to smallpox, although with notably lower mortality. This virus is clinically relevant because it is endemic to western and central Africa, with outbreaks in the Western Hemisphere related to the exotic pet trade and international travel. Transmission can occur through contact with bodily fluids, skin lesions, or respiratory droplets of infected animals directly or indirectly via contaminated fomites. Although humanto-human transmission has previously been limited, mathematical modeling in the context of decreasing herd immunity to orthopoxviruses reflects an increasing threat of disease spread between humans. The Centers for Disease Control and Prevention (CDC) recommends isolation in a negative pressure room and standard, contact, and droplet precautions in the healthcare setting with escalation to airborne precautions if possible. Following viral entry from any route (oropharynx, nasopharynx, or intradermal), the monkeypox virus replicates at the inoculation site then spreads to local lymph nodes. Next, an initial viremia leads to viral spread and seeding of other organs. This represents the incubation period and typically lasts 7 to 14 days with an upper limit of 21 days.