Fluorescence Immunoassay Influenza A/B – Product code: SC-1408-20
Immunofluorescence test for the diagnosis of the Influenza A and Influenza B virus on samples of nasopharyngeal swab, throat swab or nasal aspirate with the use of the Immunofluorescence Analyzer. For professional in vitro diagnostic use only. The Influenza A + B Cassette Test (Swab/Nasal Aspirate) is designed for the in vitro detection of influenza A and B antigens on nasopharyngeal swab samples, throat swabs or nasal aspirate. It is intended to assist in the rapid differential diagnosis of viral infections of influenza A and B. Influenza is an acute, highly contagious viral infection of the respiratory tract. It is a highly transmissible contagious disease through coughing and sneezing from suspended droplets containing the live virus1. The peak of the flu usually occurs during the winter and autumn months each year. Type A viruses are usually more prevalent than type B and associated with more serious influenza outbreaks, while type B infections are usually milder. The gold standard for laboratory diagnosis is culture at 14 days with one of a variety of cell lines that can support the growth of the influenza virus2. Cell cultures have limited clinical utility, since the results are obtained too late in the clinical course for an effective intervention on the patient. The Reverse Transcriptase Polymerase Chain Reaction (RT_PCR) is a newer and generally more sensitive culture method with better detection rates than a 2-23% culture. However, RT-PCR is expensive, complex and must be performed in specialized laboratories. The rapid test for Influenza A + B (Swab/Nasal Aspirate) qualitatively identifies the presence of influenza A and / or B antigen on samples of nasopharyngeal swab, throat swab or nasal aspirate, providing results in 15 minutes. The test uses specific antibodies for Influenza A and Influenza B to selectively identify the antigen of Influenza A and / or B on nasopharyngeal swab, throat swab or nasal aspirate samples. The cassette test for Influenza A + B (Swab/Nasal Aspirate) identifies the nucleopreoteins of Influenza A and B based on immunofluorescence. The sample moves across the strip from the sample pad to the absorbent pad. If the sample contains Influenza A or B nucleoproteins, it attaches to the fluorescent beads conjugated to anti-Influenza A and / or anti-Influenza B antibodies. Then the compound is captured by the capture antibodies placed on the nitrocellulose membrane (Test line ). The concentration of Influenza A and / or Influenza B in the sample is directly proportional to the intensity of the fluorescent signal captured on the T line which can be read by the SCREEN® Analyzer. The result of the Influenza A and Influenza B test will appear on the screen of the SCREEN® Analyzer
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