Fluorescence Immunoassay Hba1C – Product code: SC-1347-20
Rapid test for measuring the HbA1c (glycated hemoglobin) value in whole blood using the Immunofluorescence Analyzer. For professional in vitro diagnostic use only. The HbA1c Cassette Test (Whole Blood) is based on immunofluorescence for the quantitative measurement of HbA1c in whole blood. Measurement of HbA1c is recommended as a long-term marker of metabolic control in people with diabetes mellitus. This test can be used as an aid in the diagnosis of diabetes and in the identification of patients potentially at risk of developing diabetes. Human erythrocytes are freely permeable to glucose. A slow, constant non-enzymatic process takes place within each erythrocyte between hemoglobin A and various sugars. The resulting product is known as glycated hemoglobin or glycohemoglobin. Human erythrocytes are freely permeable to glucose. A slow, constant non-enzymatic process takes place within each erythrocyte between hemoglobin A and various sugars. The resulting product is known as glycated hemoglobin or glycohemoglobin. A chronic high blood sugar level in a person with diabetes mellitus is known to cause long-term complications over the years. It has been shown that good metabolic control, i.e. lowering the concentration of HbA1c, delays the onset and slows the progression of diabetic complications. It was concluded that HbA1c measurements can be used to diagnose diabetes mellitus. In compliance with national regulations, the HbA1c SCREEN® Test can be used to aid in the diagnosis of diabetes and as an aid in the identification of patients at risk of developing diabetes. The HbA1c (Whole Blood) Cassette Test identifies HbA1c based on immunofluorescence. The sample moves over the sample swab strip on the absorbent pad. The HbA1c present in the sample attaches to the HbA1c antibody conjugated with fluorescent microspheres. It is then captured by the hemoglobin antibody (Hb) which covers the nitrocellulose membrane. The concentration of HbA1c is proportional to the intensity of the fluorescence signal. Depending on the intensity of the two fluorescences, the SCREEN® Immunofluorescence Analyzer will calculate the value of the percentage of HbA1c in the sample.