Fluorescence Immunoassay Follicle Stimulating Hormone (Fsh) – Product code: SC-1385-20
Test for the diagnosis of follicle stimulating hormone (FSH) to identify follicle stimulating hormone (FSH) in whole blood, serum or plasma with the use of the Immunofluorescence Analyzer. For professional in vitro diagnostic use only. The FSH Cassette Test (Whole Blood/Serum/Plasma) is designed for the in vitro quantitative determination of follicle stimulating hormone (FSH) in whole blood, serum or plasma as an aid in the diagnosis of menopause. Menopause is the permanent cessation of menstruation but is usually not scientifically diagnosed until a full year after the interruption of the menstrual cycle in women. The period leading up to menopause and the 12 months thereafter are known as perimenopause. Many women during this period experience some symptoms such as hot flashes, irregular menstrual cycles, sleep problems, vaginal dryness, hair loss, anxiety and mood swings, short-term memory loss and fatigue. The onset of perimenopause is caused by changes in the levels of hormones in the female body that regulate the menstrual cycle. As the body produces less and less estrogen, the production of FSH increases, which normally regulates the development of eggs in women. Therefore, testing for FSH can help determine if a woman is in the perimenopausal phase. If a woman knows she is perimenopause she can take the necessary actions to stay healthy and avoid the risks associated with menopause, which include osteoporosis, high blood pressure and cholesterol, and an increased risk of heart disease4,5. The FSH Cassette Test is a rapid test that quantitatively detects the level of FSH in whole blood, serum or plasma samples. The test uses a combination of antibodies including an anti-FSH monoclonal antibody to selectively detect high levels of FSH. The minimum detection level is 10mlU/mL. The FSH Cassette Test (Whole Blood/Serum/Plasma) is based on immunofluorescence for the detection of human follicle-stimulating hormone FSH in whole blood/serum/plasma to determine the onset of menopause in women. The sample moves across the strip from the sample pad to the absorbent pad. If the sample contains FSH, it attaches to the fluorescent beads conjugated to anti-FSH antibodies. Then the compound is captured by the capture antibodies placed on the nitrocellulose membrane (Test line). The concentration of FSH in the sample is directly proportional to the intensity of the fluorescent signal captured on the T-line. Depending on the intensity of the fluorescence on the test and the standard curve, the concentration of FSH in the sample is calculated by the SCREEN® Analyzer to show the FSH concentration in the sample.